同商品型号列表:
产品基本说明:
6β-Hydroxy Cortisol-d4:sc-217394 CAS号码: 3078-34-0 (unlabeled) |
产品介绍:
存储
Store at -20° C
介绍
Labeled metabolite of Cortisol.
仅限于研究用
Not Intended for Diagnostic or Therapeutic Use.
参考文献
Dossing, M., et al.: Eur. J. Clin. Pharmacol., 25, 215
1. PRODUCT AND COMPANY IDENTIFICATION
Product Name: 6β-Hydroxy Cortisol-d4
Product Number: sc-217394
Supplier: Santa Cruz Biotechnology, Inc.
2145 Delaware Avenue
Santa Cruz, CA 95060
800.457.3801 or 831.457.3800
Emergency: ChemWatch
Within the US & Canada: 877-715-9305
Outside the US & Canada: +800 2436 2255 (1-800-CHEMCALL) or call +613 9573 3112
2. HAZARDS IDENTIFICATION
WHMIS Classification
D2A Very Toxic Material Causing Other Toxic Effects Teratogen
HMIS Classification
Health hazard: 1
Chronic Health Hazard: *
Flammability: 0
Physical hazards: 0
Target Organs
Immune system, Pituitary, Adrenal cortex
Potential Health Effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Ingestion May be harmful if swallowed.
GHS Classification
Reproductive toxicity (Category 2)
GHS Label elements, including precautionary statements
Signal word Warning
Hazard statement
H361 Suspected of damaging fertility or the unborn child.
Precautionary statements
P201 Obtain special instructions before use.
P281 Use personal protective equipment as required.
P308/P313 If exposed or concerned: Get medical advice/attention.
GHS Label Pictogram
3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonym: (6β,11β)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione-d4
Molecular Weight: 382.48
Molecular Formula: C21H26D4O6
CAS Registry #: 3078-34-0 (unlabeled)
4. FIRST AID MEASURES
General Advice
Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
5. FIRE FIGHTING MEASURES
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid dust or aerosol formation. Avoid breathing vapors, mist or gas. Ensure
adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous
earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
Keep in suitable, closed containers for disposal.
7. HANDLING AND STORAGE
Avoid contact with skin and eyes.
Avoid formation of dust or aerosols. Provide appropriate exhaust ventilation at places where dust/aerosol is
formed. Normal measures for preventative fire protection.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Store at -20º C.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Contains no substances with occupational exposure limit values.
Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type
N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the
sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching
glove''s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in
accordance with applicable laws and good laboratory practices. Wash and dry hands.
Eye protection
Face shield or safety glasses. Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin and body protection
Complete suit protecting against chemicals, if needed after risk assessment. The type of protective equipment
must be selected according to the concentration and amount of the dangerous substance at the specific
workplace.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the
end of workday.
Specific engineering controls
Use mechanical exhaust or laboratory fumehood to avoid exposure.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form Solid pH N/A
Melting point 193-201º C Boiling point N/A
Flash point N/A Ignition temperature N/A
Lower explosion limit N/A Upper explosion limit N/A
Vapor pressure N/A Density N/A
Water solubility N/A
10. STABILITY AND REACTIVITY
Chemical stability
Stable under recommended storage conditions
Conditions to avoid
no data available
Material to avoid
Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions: carbon oxides
11. TOXICOLOGICAL INFORMATION
Acute toxicity
no data available
Irritation and corrosion
Sever eye irritant
Sensitization
no data available
Reproductive toxicity/Teratogenicity
Presumed human reproductive toxicant/teratogen
Additional information
RTECS: not listed
Carcinogenicity
IARC: Not classified as a known, possible or probable carcinogen by IARC.
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Ingestion May be harmful if swallowed.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
12. ECOLOGICAL INFORMATION
Toxicity Persistence and degradability
no data available no data available
Bioaccumulative potential Mobility in soil
no data available no data available
PBT and vPvB assessment Other adverse effects
no data available no data available
13. DISPOSAL CONSIDERATIONS
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional
waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
14. TR